Predictors of 1- and 12-month mortality in bifurcation coronary intervention: a contemporary perspective

Area of Science:

• Cardiology
• Interventional Cardiology

Background:

• Bifurcation percutaneous coronary intervention (PCI) is a common procedure.
• There is a lack of definitive evidence for optimal strategies in complex bifurcation PCI.
• Understanding real-world outcomes is crucial for improving patient care.

Purpose of the Study:

• To identify factors associated with 1- and 12-month mortality after bifurcation PCI.
• To analyze outcomes in a large cohort from a tertiary center in Wales, UK.

Main Methods:

• Retrospective analysis of 732 bifurcation PCI cases performed between 2017 and 2021.
• Data collected on patient demographics, clinical presentation, procedural details, and outcomes.

Main Results:

• The study included 732 patients (mean age 69, 25% female), with 67% presenting with acute coronary syndrome (ACS).
• 30-day and 12-month mortality rates were 1.9% and 8.2%, respectively.
• Factors associated with mortality included age, diabetes, smoking, and renal failure. The choice between provisional and two-stent strategies did not impact mortality or target lesion revascularization (TLR).

Conclusions:

• Real-world outcomes of bifurcation PCI highlight the importance of patient selection and procedural planning.
• Awareness of associated mortality factors can guide technique selection and informed patient consent.
• Further research may refine strategies for complex bifurcation interventions.