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Updated: Jul 23, 2025

Robotic Central Pancreatectomy with Roux-en-Y Pancreaticojejunostomy
Published on: November 20, 2021
The Brescia Internationally Validated European Guidelines on Minimally Invasive Pancreatic Surgery (EGUMIPS)
Mohammad Abu Hilal1, Tess M E van Ramshorst1,2,3, Ugo Boggi4
1Department of General Surgery, Istituto Ospedaliero Fondazione Poliambulanza, Brescia, Italy.
Objective:
To develop and update evidence-based and consensus-based guidelines on laparoscopic and robotic pancreatic surgery.
Summary Background Data:
Minimally invasive pancreatic surgery (MIPS), including laparoscopic and robotic surgery, is complex and technically demanding. Minimizing the risk for patients requires stringent, evidence-based guidelines. Since the International Miami Guidelines on MIPS in 2019, new developments and key publications have been reported, necessitating an update.
Methods:
Evidence-based guidelines on 22 topics in 8 domains were proposed: terminology, indications, patients, procedures, surgical techniques and instrumentation, assessment tools, implementation and training, and artificial intelligence. The Brescia Internationally Validated European Guidelines on Minimally Invasive Pancreatic Surgery (EGUMIPS, September 2022) used the Scottish Intercollegiate Guidelines Network (SIGN) methodology to assess the evidence and develop guideline recommendations, the Delphi method to establish consensus on the recommendations among the Expert Committee, and the AGREE II-GRS tool for guideline quality assessment and external validation by a Validation Committee.
Results:
Overall, 27 European experts, 6 international experts, 22 international Validation Committee members, 11 Jury Committee members, 18 Research Committee members, and 121 registered attendees of the 2-day meeting were involved in the development and validation of the guidelines. In total, 98 recommendations were developed, including 33 on laparoscopic, 34 on robotic, and 31 on general MIPS, covering 22 topics in 8 domains. Out of 98 recommendations, 97 reached at least 80% consensus among the experts and congress attendees, and all recommendations were externally validated by the Validation Committee.
Conclusions:
The EGUMIPS evidence-based guidelines on laparoscopic and robotic MIPS can be applied in current clinical practice to provide guidance to patients, surgeons, policy-makers, and medical societies.
Insights
Updated European guidelines for minimally invasive pancreatic surgery (MIPS) were developed using robust methods. These evidence-based recommendations for laparoscopic and robotic procedures aim to enhance patient safety and surgical practice.
Area of Science:
- Surgical Oncology
- Minimally Invasive Surgery
- Evidence-Based Medicine
Background:
- Minimally invasive pancreatic surgery (MIPS), encompassing laparoscopic and robotic approaches, presents significant technical challenges.
- Existing guidelines require updating due to advancements and new publications since the 2019 International Miami Guidelines.
- Establishing stringent, evidence-based guidelines is crucial for minimizing patient risks in complex pancreatic procedures.
Purpose of the Study:
- To develop and update evidence-based and consensus-based guidelines for laparoscopic and robotic pancreatic surgery.
- To address 22 key topics across 8 domains relevant to MIPS, including AI and training.
Main Methods:
- Utilized the Scottish Intercollegiate Guidelines Network (SIGN) methodology for evidence assessment and recommendation development.
- Employed the Delphi method for expert consensus building and the AGREE II-GRS tool for guideline quality assessment.
- Involved a multidisciplinary expert committee, validation committee, and international experts in guideline development and validation.
Main Results:
- Developed 98 recommendations covering general, laparoscopic, and robotic MIPS across 22 topics.
- Achieved over 80% consensus on 97 out of 98 recommendations from experts and attendees.
- All recommendations underwent external validation by a dedicated Validation Committee.
Conclusions:
- The Brescia Internationally Validated European Guidelines on Minimally Invasive Pancreatic Surgery (EGUMIPS) provide current, evidence-based guidance.
- These guidelines are applicable in clinical practice to inform patients, surgeons, policymakers, and medical societies.
- EGUMIPS promotes standardized, safe, and effective minimally invasive pancreatic surgery.
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