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Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
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Robust real-time imaging through flexible multimode fibers.

Abdullah Abdulaziz1, Simon Peter Mekhail2, Yoann Altmann3

  • 1School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, EH14 4AS, UK. a.abdulaziz@hw.ac.uk.

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|July 14, 2023
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Summary
This summary is machine-generated.

This study introduces a novel imaging system using a single flexible optical fiber that reconstructs clear images from distorted speckle patterns. The system is robust to bending and does not need distal end feedback, enabling new flexible imaging possibilities.

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Area of Science:

  • Optics and Photonics
  • Biomedical Imaging
  • Machine Learning

Background:

  • Conventional endoscopes use fiber bundles, limiting flexibility.
  • Single multimode optical fibers (MMFs) offer potential miniaturization but suffer from image distortion (speckle patterns) due to modal dispersion and coupling.
  • Fiber bending further complicates MMF imaging, hindering flexible applications.

Purpose of the Study:

  • To develop a real-time imaging system using flexible MMFs that is robust to bending.
  • To demonstrate image reconstruction from speckle patterns without distal end feedback.
  • To enable MMFs for flexible imaging applications previously hindered by bending-induced distortions.

Main Methods:

  • Utilized a single multimode optical fiber (MMF) for image transmission.
  • Employed a variational autoencoder (VAE) for reconstructing images from speckle patterns.
  • Trained the VAE to be robust to changes in fiber bend configurations.

Main Results:

  • Successfully reconstructed images from speckle patterns transmitted through a 300 mm MMF.
  • Demonstrated image recovery even when the fiber bend configuration was outside the training set.
  • The system showed robustness to a 50° change in fiber bend and an 8 cm range of movement.

Conclusions:

  • The proposed system enables real-time imaging through flexible MMFs, overcoming limitations of bending-induced speckle distortions.
  • The VAE-based approach allows for robust image reconstruction without needing distal end information.
  • This technology has potential for advanced flexible endoscopic imaging and other applications requiring miniaturized optical systems.