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Type IV pili are involved in phenotypes associated with Clostridioides difficile pathogenesis

Zirou Ouyang1, Hanlin Zhao2, Min Zhao1

  • 1Hebei Provincial Center for Clinical Laboratories, The Second Hospital of Hebei Medical University, Shijiazhuang City, Hebei Province, China.

Critical Reviews in Microbiology
|July 15, 2023
PubMed
Summary

Clostridioides difficile uses Type IV pili (T4P) for intestinal persistence and spreading. This review details how T4P contribute to C. difficile pathogenesis, aggregation, and biofilm formation.

Keywords:
Clostridioides difficileadherencebiofilm formationcyclic diguanylatetype IV pili

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