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Updated: Jul 23, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Utility of right adrenal signature veins in venous sampling for primary aldosteronism
Zhenglin Shen1, Shaoyong Xu2,3, Siyu Guan4
1Hybrid Operation Room, Xiangyang Central Hospital, Affiliated Xiangyang Hospital of Hubei College of Arts and Sciences, Xiangyang, Hubei, China.
Background:
This study aimed to identify the appropriate signature veins for the right adrenal gland using a 3D model fused with adrenal venography images and to verify their accuracy through the selectivity index (SI) >2.
Methods:
We analyzed the right adrenal venography images of 41 patients who underwent adrenal venous sampling (AVS). These images were merged with a 3D structure of the adrenal gland to identify the signature veins of the right adrenal gland. We then used the signature veins observed during adrenal venography to determine the optimal position of the catheter tip during AVS for 53 other patients. Finally, we verified the accuracy of this method according to the SI.
Results:
We successfully fused the 3D models of 41 cases with adrenal venography images. We identified the trunk branch type as the major venous morphology in the right anterior oblique at degrees of 30 (38 cases, 92.7%). In addition, the central vein, brush vein, uvula vein, and capsular vein were identified as signature veins for the right AVS. The accuracy of AVS was 100% in the other 53 patients, as verified by an SI >2.
Conclusions:
Our study identified the right adrenal signature veins, including the previously overlooked uvula vein, which can be used to determine the position of the catheter tip and improve the success rate of AVS.
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