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The biological sample collection of the OFSEP French MS registry: An essential tool dedicated to researchers
Guillaume Brocard1, Romain Casey1, Nathalie Dufay2
1Lyon University, University Claude Bernard Lyon 1, F-69000, Lyon, France; Hospices Civils de Lyon, Neurology Department, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation, F-69677, Bron, France; Observatoire Français de la Sclérose en Plaques, Centre de Recherche en Neurosciences de Lyon, INSERM 1028 and CNRS UMR 5292, F-69003, Lyon, France; EUGENE DEVIC EDMUS Foundation against Multiple Sclerosis, State-Approved Foundation, F-69677, Bron, France.
Abstract:
Today's medicine strives to be personalized, preventive, predictive and participatory. This implies to have access to multimodal data to better characterize patients groups and to combine clinical and imaging data with high-quality biological samples. Collecting such data is one of the objectives of the Observatoire français de la sclérose en plaques (OFSEP), the French MS registry. On December 2022, the OFSEP biocollection includes 4,888 patients with scientific characteristics and about 90,000 samples. Thanks to its richness, this biocollection open for the scientific community, contributes to address unmet needs in MS through identification of multiomics determinants of MS activity, progression and secondary effects.
