Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decoding the association between microorganisms and autoimmunity: a multifaceted review of evidence on specific pathogens that trigger autoimmune diseases.

Clinical and experimental medicine·2026
Same author

Iron-based magnetic nanoplatforms for immune microenvironment remodeling and cancer immunotherapy: progress and prospects.

Journal of nanobiotechnology·2026
Same author

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway.

Phytotherapy research : PTR·2026
Same author

Integrating machine learning of bulk and single cell RNA data to characterize immune mechanism of m6A related mitophagy genes in malignant gastric cancer.

Computer methods and programs in biomedicine·2026
Same author

A Unique Perspective on Auto-reactive Antibody Production in Autoimmune Disease Induced by Microbiome.

Frontiers in bioscience (Landmark edition)·2026
Same author

Proximity-Based Phospho-Interactome (Prob-PhI) Characterization Reveals Distinct Signaling Activities of MEK1 and MEK2.

Analytical chemistry·2026

Related Experiment Video

Updated: Jul 23, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.5K

Hydrogel-enabled mechanically active wound dressings.

Le Chang1, Huicong Du2, Feng Xu3

  • 1Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, Xi'an 710068, China; Shaanxi Engineering Research Center of Cell Immunology, Shaanxi Provincial People's Hospital, Xi'an 710068, China.

Trends in Biotechnology
|July 15, 2023
PubMed
Summary

Mechanically active dressings (MADs) utilize self-contractile hydrogels to improve wound repair by mechanically contracting the wound bed, offering a promising alternative to conventional treatments.

Keywords:
hydrogelswearable mechanical loadingwound care

More Related Videos

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

464
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

352

Related Experiment Videos

Last Updated: Jul 23, 2025

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde
07:04

Synthesis of Strong Adhesive Hydrogel, Gelatin O-Nitrosobenzaldehyde

Published on: November 11, 2022

2.5K
Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

Published on: May 2, 2025

464
Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management
09:17

Optimizing Extracellular Vesicle Delivery Using a Core-Sheath 3D-Bioprinted Scaffold for Chronic Wound Management

Published on: February 28, 2025

352

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Wound Healing Research

Background:

  • Effective wound repair remains a significant clinical challenge.
  • Conventional dressings often lead to detrimental healing outcomes.
  • Mechanically active dressing (MAD) is an emerging wound care technology.

Purpose of the Study:

  • To review the development of mechanically active dressing (MAD) technology.
  • To elucidate the mechanisms of mechanically modulated wound healing.
  • To discuss hydrogel design for MAD fabrication and clinical translation.

Main Methods:

  • Systematic review of mechanically active dressing technology.
  • Analysis of hydrogel design principles for MAD fabrication.
  • Discussion on clinical translation and personalized wound care.

Main Results:

  • MAD employs self-contractile hydrogels to mechanically contract the wound bed.
  • MAD demonstrates improved wound healing rates with limited side effects.
  • Hydrogel design is crucial for effective MAD fabrication.

Conclusions:

  • MAD technology shows significant promise for advancing wound care.
  • Further research in hydrogel design and clinical application is needed.
  • Personalized wound care strategies can be realized through MAD advancements.