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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Cardiac Infections

Jasim Jaleel1, Prateek Kaushik1, Chetan Patel1

  • 1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Nuclear Medicine : IJNM : the Official Journal of the Society of Nuclear Medicine, India
|July 17, 2023
PubMed

Insights

Diagnosing cardiac infections like infective endocarditis remains difficult. 18F-FDG PET/CT offers a valuable tool for identifying active infections and aiding diagnosis when other methods fall short.

Area of Science:

  • Nuclear Medicine
  • Cardiology
  • Infectious Diseases

Background:

  • Cardiac infections, including infective endocarditis and device infections, present diagnostic challenges despite high mortality rates.
  • Conventional imaging like echocardiography, CT, and MRI often fail to confirm active infection or detect extracardiac findings.
  • Current guidelines recommend 18F-FDG PET/CT for suspected prosthetic valve infective endocarditis.

Purpose of the Study:

  • To demonstrate the diagnostic utility of 18F-FDG PET/CT in various cardiac infection scenarios.
  • To highlight how 18F-FDG PET/CT aids in resolving complex diagnostic dilemmas in cardiology.
  • To showcase the application of 18F-FDG PET/CT in infective endocarditis, cardiac device infections, and coronary stent infections.

Main Methods:

  • This pictorial essay reviews cases utilizing 18F-FDG PET/CT.
  • The study focuses on patients with suspected or confirmed cardiac infections.
  • Imaging findings from 18F-FDG PET/CT are correlated with clinical outcomes.

Main Results:

  • 18F-FDG PET/CT proved effective in diagnosing varied cases of infective endocarditis.
  • The modality successfully identified infections associated with cardiac implantable electronic devices.
  • 18F-FDG PET/CT was instrumental in diagnosing coronary stent infections and resolving diagnostic uncertainties.

Conclusions:

  • 18F-FDG PET/CT is a powerful imaging technique for diagnosing cardiac infections.
  • Its ability to detect active infection and extracardiac findings surpasses conventional methods.
  • 18F-FDG PET/CT should be considered a key tool in the workup of complex cardiac infections.

Keywords:
Cardiac implantable electronic devicefluorodeoxyglucoseinfectioninfective endocarditispositron emission tomography-computed tomographystent infection

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