Rebound Catatonia Associated With Injectable Paliperidone
Bamidele O Johnson1, Godwin Orji1, Olayemi O Johnson2
1Psychiatry, Interfaith Medical Center, Brooklyn, USA.
Cureus
|July 17, 2023
Summary
Paliperidone, an antipsychotic, can paradoxically induce catatonia in schizophrenia patients. This case highlights the rare but serious risk of medication-induced catatonia, necessitating careful monitoring.
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Paliperidone is an atypical antipsychotic used for schizophrenia, schizoaffective disorder, and bipolar disorder.
- It functions by blocking dopamine D2 receptors.
- Adverse effects include extrapyramidal symptoms, weight gain, and metabolic issues, with rare but severe instances like catatonia.
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