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Updated: Jul 23, 2025
11:18
Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
Published on: January 22, 2011
16.1K
"A tumour registry initiative".
Rajesh Nair1, Bhavna Nayal2, Saurabh Beedkar1
1Department of Neurosurgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.
World Neurosurgery: X
|July 17, 2023
Summary
This study analyzed 158 pediatric brain tumors in South India, finding astrocytomas most common. Pediatric central nervous system tumors show a male predominance and occur more frequently in the second decade of life.
Area of Science:
- Neuro-oncology
- Pediatric Neurology
- Epidemiology
Background:
- Limited published data exists on the epidemiological profile of pediatric brain tumors in India.
- This study addresses the need for localized data on pediatric central nervous system (CNS) tumor characteristics.
Purpose of the Study:
- To conduct a retrospective analysis of the histological spectrum of pediatric CNS tumors.
- To describe the frequency and characteristics of 158 pediatric CNS tumors operated between 2015 and 2021.
Main Methods:
- Retrospective analysis of 158 pediatric patients (<18 years) with primary brain tumors.
- Tumor classification based on the 4th edition of the World Health Organization (WHO) classification of CNS tumors.
Main Results:
- Pediatric CNS tumors represented 8.5% of all intracranial tumors operated.
- Astrocytomas, glioneuronal, and neuronal tumors were most common (45.6%), followed by embryonal tumors (19.6%) and craniopharyngiomas (15.4%).
- Supratentorial tumors (58.2%) were more frequent than posterior fossa (34.6%) or spinal tumors (7.6%).
Conclusions:
- Pediatric CNS tumors are more prevalent in boys and during the second decade of life.
- Astrocytomas are the most frequent pediatric brain tumors, followed by medulloblastomas and craniopharyngiomas.
- The tumor distribution aligns with findings from other Indian and Western centers.
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