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Catecholamine-induced Takotsubo syndrome: a case series
Nicola Campana, Alessandra Gioi, Maria Francesca Marchetti1
1Department of Medical Sciences and Public Health, Cardiology Unit, University Hospital Duilio Casula-Azienda Ospedaliero-Universitaria di Cagliari, University of Cagliari, SS 554 4,5 km, Cagliari 09042, Italy.
Catecholamine-induced Takotsubo Syndrome (cat-TS) can occur after medical procedures involving catecholamine administration. Early screening and echocardiograms are crucial for prompt diagnosis and management of cat-TS.
Area of Science:
- Cardiology
- Critical Care Medicine
Background:
- Catecholamine-induced Takotsubo Syndrome (cat-TS) is a subtype of stress-induced cardiomyopathy.
- It is characterized by acute cardiac dysfunction following catecholamine administration, often presenting with apical sparing on echocardiography.
Observation:
- Two cases of cat-TS are presented: a 78-year-old male post-oral cancer surgery and a 64-year-old female post-hysteropexy.
- Both patients received catecholamines during procedures, subsequently developing symptoms consistent with myocardial impairment, including elevated troponin and wall motion abnormalities.
Findings:
- Angiography revealed no significant coronary stenoses in either patient, ruling out obstructive coronary artery disease.
- Echocardiography and cardiac MRI confirmed midventricular akinesia/hypokinesia with apical sparing, and rapid recovery of function was observed.
Implications:
- Highlights the importance of vigilant monitoring for myocardial impairment after catecholamine administration.
- Emphasizes the role of clinical assessment, ECG, troponin testing, and prompt echocardiography in early cat-TS detection and management to prevent complications.
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