Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Critical corneal oxygen values: a summary.

B A Weissman

    Journal of the American Optometric Association
    |August 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    This study determined the critical oxygen levels needed for hydrogel contact lenses during wear. It established the required oxygen transmissibility (Dk/L) for comfortable open-eye and extended-wear conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Deterioration in brain and heart functions following a single sub-lethal (0.8 LCt50) inhalation exposure of rats to sarin vapor: a putative mechanism of the long term toxicity.

    Toxicology and applied pharmacology·2011
    Same author

    Ontogenesis of enkephalin and humoral endorphin in the rat brain.

    Neurochemistry international·2010
    Same author

    Measurement of NO and NO synthase.

    Current protocols in neuroscience·2008
    Same author

    Acute and long-lasting cardiac changes following a single whole-body exposure to sarin vapor in rats.

    Toxicological sciences : an official journal of the Society of Toxicology·2005
    Same author

    Are we going to Scarborough fair. . . Or perhaps St. Elsewhere?

    Optometry (St. Louis, Mo.)·2004
    Same author

    Factors associated with corneal scarring in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study.

    Cornea·2000
    Same journal

    Visual skills profiles.

    Journal of the American Optometric Association·2014
    Same journal

    Dark adaptation and night blindness.

    Journal of the American Optometric Association·2014
    Same journal

    Scleral tonometry.

    Journal of the American Optometric Association·2014
    Same journal

    Staying in shape: the different roads to fitness for busy optometrists.

    Journal of the American Optometric Association·2000
    Same journal

    Hiring a new optometrist? Be prepared!

    Journal of the American Optometric Association·2000
    Same journal

    Late traumatic intraocular lens extrusion after penetrating keratoplasty.

    Journal of the American Optometric Association·2000
    See all related articles

    Area of Science:

    • Ophthalmology
    • Biomaterials Science
    • Optometry

    Background:

    • Contact lens wear requires adequate oxygen supply to the cornea.
    • Previous studies have varied in their estimations of oxygen needs.
    • Hydrogel contact lenses are widely used, necessitating clear oxygenation standards.

    Purpose of the Study:

    • To establish a summary critical human pre-corneal oxygen tension.
    • To determine the required oxygen transmissibility (Dk/L) for hydrogel contact lenses.
    • To provide estimations for both open-eye and closed-eye (extended wear) conditions.

    Main Methods:

    • Collected and analyzed data from multiple previous studies.
    • Remeasured hydrogel contact lens oxygen transmissibilities (Dk/L) at ocular temperature.

    Related Experiment Videos

  • Calculated critical pre-corneal oxygen tension and required Dk/L values.

    • Main Results:

    • Established a summary critical human pre-corneal oxygen tension of 30 mmHg.
    • Determined the required Dk/L for open-eye conditions to be 18 x 10(-9) cm2 ml O2/sec ml mmHg.
    • Performed estimations for closed-eye (extended wear) oxygen requirements.

    Conclusions:

    • The study provides essential benchmarks for hydrogel contact lens oxygen performance.
    • Findings are crucial for designing safer and more comfortable contact lenses.
    • The data supports the development of lenses suitable for both daily and extended wear.