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Updated: Jul 23, 2025

In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats
Published on: September 27, 2017
Quantitative analysis of the distribution of the myenteric plexus in the rabbit large intestine
Tetsuhito Kigata1,2, Tatsuhiro Koyama2, Xizi Lu2
1Department of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, Japan.
Abstract:
Rabbit large intestine has a segment-specific morphology and motility. However, the morphological features of the myenteric plexus, which controls intestinal motility, have not been characterized in each large intestinal segment. We investigated the myenteric plexus morphology in the rabbit large intestine using protein gene product 9.5 immunohistochemistry in whole-mount preparations. The tenial part of the first and second segments of the proximal colon had the most well developed myenteric plexus, while the caecum had the least. These findings suggest different neuronal control over the motility of each intestinal segment, thereby providing a fundamental understanding of the rabbit enteric nervous system.
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