Related Experiment Video
Updated: Jul 23, 2025
04:44
Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
352
Older age bipolar disorder
Alexandra J M Beunders1,2,3, Melis Orhan4, Annemiek Dols5
1GGZ inGeest Specialized Mental Healthcare.
Current Opinion in Psychiatry
|July 17, 2023
Summary
Older age bipolar disorder (OABD) is complex, with higher risks of cognitive issues and physical health problems. An integrated care approach is recommended for better psychosocial functioning and quality of life in OABD patients.
Area of Science:
- Geriatric Psychiatry
- Neuroscience
- Clinical Psychology
Background:
- Older age bipolar disorder (OABD) affects individuals aged 50 and above.
- Limited evidence-based guidelines exist specifically for OABD.
- Recent literature provides new insights into OABD management.
Approach:
- Synthesizing existing literature up to January 1, 2021.
- Incorporating the latest research published since January 1, 2021.
- Reviewing key themes including diagnosis, clinical course, functioning, cognition, comorbidities, and pharmacotherapy.
Key Points:
- OABD presents unique challenges, including increased cognitive deficits and physical comorbidities.
- Traditional bipolar disorder subtypes (BD-I, BD-II, EOBD, LOBD) lack clinical relevance in OABD.
- Lithium treatment remains a viable option for older adults with bipolar disorder.
Conclusions:
- OABD requires an integrative care model addressing cognitive and physical health.
- Focus on improving psychosocial functioning and quality of life is crucial.
- Future research should utilize validated scales for essential data collection.
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