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Rab11-FIP4 interacts with ARF5 to promote cancer stemness in hepatocellular carcinoma

Feifeng Song1,2, Qi Zhang1, Xixuan Lu1

  • 1Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, China.

Journal of Physiology and Biochemistry
|July 17, 2023
PubMed
Summary

Rab11-FIP4 promotes hepatocellular carcinoma (HCC) stemness and sorafenib resistance by interacting with ARF5. Targeting Rab11-FIP4 may offer a new therapeutic strategy for HCC.

Keywords:
ADP-ribosylation factor 5Cancer stemnessDrug resistanceHepatocellular carcinomaRab11-family interacting protein 4

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