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Male Sexual Response: Erection & Ejaculation

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...

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[Neuromodulation therapies for premature ejaculation: Progress in studies].

Qi-Gang Zheng¹, Jia-Cheng Li¹, Xiao-Jun Huang¹

¹Department of Urology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310000, China .

Zhonghua Nan Ke Xue = National Journal of Andrology

|July 17, 2023

Summary

This summary is machine-generated.

Neuromodulation therapies offer new options for treating premature ejaculation, addressing limitations of oral medications. This review explores nerve blocks, local anesthetics, and injections for complex male sexual dysfunction.

Keywords:

premature ejaculation botulinum toxin dorsal nerve block ejaculation reflex hyaluronic acid injection local anesthetics

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Area of Science:

Urology
Sexual Medicine
Neuroscience

Context:

Premature ejaculation (PE) is a prevalent male sexual dysfunction with complex pathophysiology.
Current first-line oral treatments for PE face challenges like drug resistance and adverse effects.

Purpose:

To review emerging neuromodulation therapies for premature ejaculation.
To provide treatment references for diverse PE cases.

Summary:

This review examines neuromodulation techniques for PE, including dorsal nerve block, local anesthetics, hyaluronic acid injections, and botulinum toxin.
These therapies offer alternatives to oral medications by targeting the underlying neurological and muscular mechanisms of PE.

Impact:

Highlights novel therapeutic strategies beyond conventional oral treatments for PE.
Aims to guide clinicians in selecting appropriate neuromodulation techniques for individual PE patients.