Clinical Efficacy of Pre-Hospital Electrocardiogram Transmission in Patients Undergoing Primary Percutaneous Coronary
Keiichi Kohashi1, Masataka Nakano1, Takaaki Isshiki1
1Department of Cardiology, Ageo Central General Hospital.
Insights
Pre-hospital electrocardiogram (PH-ECG) transmission by emergency medical services (EMS) significantly reduces door-to-balloon time and 30-day mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (pPCI).
Area of Science:
- Cardiology
- Emergency Medicine
- Health Services Research
Background:
- Primary percutaneous coronary intervention (pPCI) is a key treatment for ST-segment elevation myocardial infarction (STEMI).
- Pre-hospital electrocardiogram (PH-ECG) transmission by emergency medical services (EMS) can expedite reperfusion therapy.
- Limited data exist on the specific clinical benefits of PH-ECG at individual hospital levels.
Purpose of the Study:
- To investigate the clinical efficacy of PH-ECG transmission in STEMI patients undergoing pPCI.
- To evaluate the impact of PH-ECG on door-to-balloon time (D2BT) and patient mortality.
- To assess the role of EMS-provided PH-ECG information in STEMI management.
Main Methods:
- Retrospective, observational study of 237 STEMI patients undergoing pPCI.
- Patients divided into two groups: PH-ECG transmission group (n=77) and non-PH-ECG group (n=160).
- Comparison of D2BT, 30-day all-cause mortality, and outcomes stratified by GRACE score.
Main Results:
- The PH-ECG group had a significantly shorter D2BT (66 min vs. 70 min, P=0.01).
- 30-day all-cause mortality was significantly lower in the PH-ECG group (6% vs. 16%, P=0.037).
- The survival benefit was more pronounced in severely ill patients (stratified by GRACE score).
Conclusions:
- PH-ECG transmission by EMS improves survival rates for STEMI patients undergoing pPCI.
- Enhanced pre-arrival preparation through EMS information is crucial for STEMI care.
- Effective coordination between EMS and PCI-capable hospitals is essential for managing PH-ECG.
Abstract:
Rapid reperfusion by primary percutaneous coronary intervention (pPCI) is an established strategy for the treatment of patients with ST-segment elevation myocardial infarction (STEMI). Pre-hospital electrocardiogram (PH-ECG) transmission by the emergency medical services (EMS) facilitates timely reperfusion in these patients. However, evidence regarding the clinical benefits of PH-ECG in individual hospitals is limited.This retrospective, observational study investigated the clinical efficacy of PH-ECG in STEMI patients who underwent pPCI. Of a total of 382 consecutive STEMI patients, 237 were enrolled in the study and divided into 2 groups: a PH-ECG group (n = 77) and non-PH-ECG group (n = 160). Door-to-balloon time (D2BT) was significantly shorter in the PH-ECG group (66 [52-80] min), compared to the non-PH-ECG group (70 [57-88] minutes, P = 0.01). The 30-day all-cause mortality rate was 6% in the PH-ECG group, which was significantly lower than that in the non-PH-ECG group (16%) (P = 0.037, hazard ratio [HR]: 0.38, 95% CI: 0.15-0.98). This trend was particularly evident in severely ill patients when stratified by GRACE score.The use of PH-ECG improved the survival rate of STEMI patients undergoing pPCI due to the improved pre-arrival preparation based on the EMS information. Coordination between EMS and PCI-capable institutes is essential for the management of PH-ECG.
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