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[Bioinformatics analysis and key gene verification of sepsis myocardial macrophage microarray data based on GEO
1Department of Rehabilitation, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhonghua Xin Xue Guan Bing Za Zhi
|July 17, 2023
Summary
Bioinformatics identified Suppressor of cytokine signaling 3 (Socs3), Interleukin 1 receptor antagonist (Il1rn), and Chemokine C-C motif ligand 7 (Ccl7) as key genes in sepsis-induced myocardial injury. These genes were upregulated in cardiac macrophages and show potential as diagnostic and therapeutic targets.
Area of Science:
- Cardiovascular Biology
- Immunology
- Bioinformatics
