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Updated: Jul 23, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Outcomes of two different treatment modalities in mild to moderate keratoconus
Ahmed M Khalafallah1, Mohamed F Abdelkader2, Ahmed M Sabry2
1Ophthalmology Department, Faculty of Medicine, Minia University, Minia, Egypt. drahmedmaher1988@gmail.com.
Purpose:
To describe visual and refractive outcomes of intrastromal corneal ring segments (ICRS) and toric implantable collamer lenses (TICL) implantation in cases of mild and moderate keratoconus.
Methods:
A prospective descriptive interventional case series. 40 eyes were allocated into two groups. First group (20 eyes) was treated with corneal collagen crosslinking (CXL) 1 month after ICRS implantation and the second group was treated using TICL after 1 year of CXL.
Results:
Both groups showed statistically significant improvement in spherical equivalent, cylindrical refraction, uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA) over the follow-up period.
Conclusion:
Both ICRS and TICL are effective in treatment of mid and moderate keratoconus with more predictable visual results with TICL.
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