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Potential Drugs in COVID-19 Management
Amin Gasmi1, Sadaf Noor2, Alain Menzel3
1Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.
Current Medicinal Chemistry
|July 18, 2023
Summary
This review examines medications repurposed for COVID-19 treatment, including antivirals and anti-inflammatories. While promising, further clinical research is essential to confirm their efficacy and safety for SARS-CoV-2 infection.
Area of Science:
- * Infectious Diseases and Virology
- * Pharmacology and Therapeutics
Background:
- * The emergence of SARS-CoV-2 (the virus causing COVID-19) in late 2019 necessitated rapid identification of effective treatments.
- * No specific vaccines or antiviral drugs were initially available, prompting investigation into existing medications.
Purpose of the Study:
- * To systematically review the current literature on the efficacy of various repurposed drugs for treating COVID-19.
- * To analyze the potential benefits and risks of these treatments, including impacts on comorbidities like hypertension and diabetes.
Main Methods:
- * Comprehensive literature search of existing studies on COVID-19 treatments.
- * Inclusion of diverse drug classes: antivirals, anti-malarials, anti-inflammatories (NSAIDs, corticosteroids), antipyretics, antiparasitics, and statins.
Main Results:
- * Several drug classes show potential therapeutic promise against SARS-CoV-2.
- * Analysis considered both efficacy and potential adverse effects, including interactions with common health conditions.
Conclusions:
- * Repurposed medications offer potential avenues for COVID-19 treatment.
- * Definitive therapeutic efficacy requires further rigorous clinical trials and product development.
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