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Updated: Jul 23, 2025

Using Computer Vision Libraries to Streamline Nuclei Quantification
Published on: June 6, 2025
Application of Spherical Convolutional Neural Networks to Image Reconstruction and Denoising in Nuclear Medicine
Amirreza Hashemi1, Yuemeng Feng1, Arman Rahmim2
1Division of Nuclear Medicine & Molecular Imaging, Department of Radiology, Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA.
Abstract:
This work investigates use of equivariant neural networks as efficient and high-performance frameworks for image reconstruction and denoising in nuclear medicine. Our work aims to tackle limitations of conventional Convolutional Neural Networks (CNNs), which require significant training. We investigated equivariant networks, aiming to reduce CNN's dependency on specific training sets. Specifically, we implemented and evaluated equivariant spherical CNNs (SCNNs) for 2- and 3-dimensional medical imaging problems. Our results demonstrate superior quality and computational efficiency of SCNNs in both image reconstruction and denoising benchmark problems. Furthermore, we propose a novel approach to employ SCNNs as a complement to conventional image reconstruction tools, enhancing the outcomes while reducing reliance on the training set. Across all cases, we observed significant decrease in computational cost by leveraging the inherent inclusion of equivariant representatives while achieving the same or higher quality of image processing using SCNNs compared to CNNs. Additionally, we explore the potential of SCNNs for broader tomography applications, particularly those requiring rotationally variant representation.
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