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Defining Dementia Subtypes Through Neuropsychiatric Symptom-Linked Brain Connectivity Patterns
Kanhao Zhao1, Hua Xie2,3, Gregory A Fonzo4
1Department of Bioengineering, Lehigh University, Bethlehem, PA, USA.
This study reveals distinct dementia subtypes based on brain connectivity and neuropsychiatric symptoms. Identifying these neurophysiological subtypes can improve targeted dementia management and interventions.
Area of Science:
- Neuroscience
- Medical Imaging
- Psychiatry
Background:
- Dementia presents significant heterogeneity in neuropsychiatric symptoms (NPS) and neuroimaging findings.
- Understanding this heterogeneity is crucial for effective dementia management and treatment.
Conclusions:
- Findings illuminate the neuropsychiatric and functional brain heterogeneity in dementia.
- Offers insights for improved clinical management and targeted interventions.
- Highlights potential for personalized treatment strategies in dementia care.
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