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Updated: Jul 23, 2025

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Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
Published on: October 11, 2017
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Movement-related modulation in mouse auditory cortex is widespread yet locally diverse
Karin Morandell1, Audrey Yin1, Rodrigo Triana Del Rio1
1Center for Neural Science, New York University, New York, NY 10012.
Biorxiv : the Preprint Server for Biology
|July 18, 2023
Summary
Movement influences mouse auditory cortex neurons, with both suppression and enhancement of sound responses. This widespread modulation is conserved across auditory cortical fields during locomotion and other behaviors.
Area of Science:
- Neuroscience
- Auditory Neuroscience
- Systems Neuroscience
Background:
- Neurons in the mouse auditory cortex are significantly modulated by behavior, including movement.
- The auditory cortex has multiple fields with distinct sound processing roles and brain connectivity.
- Movement-related modulation varies at the single-cell level, suggesting potential differences across cortical fields.
Conclusions:
- Movement-related modulation is a widespread phenomenon in the mouse auditory cortex.
- Despite single-cell variability, the overall impact of locomotion on auditory cortex activity is similar across different fields.
- Auditory cortical modulation by movement is complex, integrating running speed and non-locomotor behaviors.
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