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Crowder titrations enable the quantification of driving forces for macromolecular phase separation

Gaurav Chauhan, Anne Bremer, Furqan Dar

    Biorxiv : the Preprint Server for Biology
    |July 18, 2023
    PubMed
    Summary

    Titrating crowders helps quantify macromolecule phase separation. This method extracts intrinsic driving forces, like saturation concentration and second virial coefficients, revealing macromolecule-solvent interactions for better cellular matter control.

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