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Updated: Jul 23, 2025

Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain

Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain

Published on: December 12, 2017

CREID - A ChemoReceptor-Effector Interaction Database.

Vincent J Peta¹, Timothy Hartman¹, Shiva Aryal²

¹Biomedical Engineering Department, University of South Dakota, Sioux Falls, SD 57107.

Biorxiv : the Preprint Server for Biology

|July 18, 2023

Summary

This summary is machine-generated.

The ChemoReceptor-Effector Interaction Database (CREID) provides bacterial chemosensory pathway data. It aids researchers in understanding chemoreceptor and effector roles in diverse environments.

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Area of Science:

Microbiology
Biochemistry
Bioinformatics

Background:

Bacterial chemosensory systems regulate responses to environmental stimuli.
Understanding chemoreceptor and effector interactions is crucial for deciphering cellular behavior.
Existing data on these interactions is fragmented, hindering comprehensive analysis.

Approach:

Developed the ChemoReceptor-Effector Interaction Database (CREID).
Integrated protein and interaction data for bacterial chemosensory pathways.
Created a user-friendly website for data access and education.

Key Points:

CREID contains data on 2,440 proteins from 7 bacterial families.
Includes 1,996 documented chemoeffector interactions.
Provides terms and information on complex chemosensory networks.

Conclusions:

CREID serves as a valuable resource for studying bacterial chemosensation.
Facilitates research and collaboration in understanding environmental responses.
Enhances knowledge of intricate biological networks through accessible data.