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Current update on anaphylaxis: anaphylaxis management in recent guidelines.

D Antolín-Amérigo1, C Vidal-Albareda1, D González de Olano1

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Anaphylaxis, a severe allergic reaction, is increasingly recognized. This review examines its definitions, epidemiology, triggers, and management guidelines, proposing new diagnostic tools.

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Area of Science:

  • Allergy and Immunology
  • Clinical Medicine

Background:

  • Anaphylaxis is a life-threatening hypersensitivity reaction that is often underdiagnosed.
  • Global incidence of anaphylaxis appears to be rising, potentially due to increased allergic disease prevalence and improved recognition.

Purpose of the Study:

  • To review current definitions, epidemiology, and triggers of anaphylaxis.
  • To explore existing guideline recommendations for anaphylaxis diagnosis and management.
  • To introduce a novel anaphylaxis calculator and review current scoring methods.

Main Methods:

  • Literature review of anaphylaxis definitions, epidemiology, triggers, and management guidelines.
  • Analysis of current diagnostic and management strategies.
  • Proposal of a new anaphylaxis calculator and review of existing scoring systems.

Main Results:

  • Anaphylaxis is underrecognized despite increasing incidence.
  • Geographical variations in incidence exist.
  • Need for localized anaphylaxis management guidelines and assessment of their effectiveness.

Conclusions:

  • Anaphylaxis management requires tailored guidelines and effective implementation strategies.
  • Novel tools like an anaphylaxis calculator may improve diagnosis and management.
  • Further research is needed to assess the impact of guidelines and scoring methods.