Related Experiment Video
Updated: Aug 2, 2026
09:29
The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies
Published on: February 12, 2015
Krypton-79m: a new radionuclide for applications in nuclear medicine
Summary
Krypton-79m (79mKr) is a novel radiotracer for lung imaging. This study demonstrates its effective production and continuous delivery for high-quality pulmonary imaging using an Anger scintillation camera.
Area of Science:
- Nuclear Medicine
- Radiochemistry
- Medical Imaging
Background:
- Krypton-79m (79mKr) is a radioisotope with potential applications in nuclear medicine.
- Effective methods for its production and delivery are crucial for clinical use.
Purpose of the Study:
- To develop and evaluate a method for producing and utilizing Krypton-79m for pulmonary imaging.
- To assess the feasibility of using 79mKr as a radiotracer for visualizing lung structures.
Main Methods:
- 79mKr was generated by bombarding bromide salt solutions with 14-MeV protons.
- Continuous gas sweeping with helium facilitated the separation and delivery of 79mKr.
- The gas mixture was inhaled by patients and imaged using an Anger scintillation camera.
Main Results:
- High yields of 79mKr (up to 200 mCi/L) were achieved.
- Pulmonary images clearly visualized the lungs, trachea, and bronchi.
- Short-lived isotopes (81mKr, 79Kr) were minimized at the point of use.
Conclusions:
- Krypton-79m can be readily produced and delivered for dynamic lung imaging.
- This technique provides good quality images of the respiratory system.
- 79mKr shows promise as a valuable radiotracer in nuclear medicine for lung imaging.
More Related Videos
![Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F55537.jpg&w=3840&q=50)
11:03Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases
Published on: May 29, 2017
09:49A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy (PRRT): 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Related Concept Videos
03:18Nuclear Stability
Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged protons together in the...
To hold positively charged protons together in the...
03:20Nuclear Transmutation
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed protons being...
01:29Positron Emission Tomography
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
01:28Isotopes and Radioisotopes
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing more...
An isotope containing more...
01:30Radiological Investigation I: X-ray and CT
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET