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Staphylococcus epidermidis-associated enterocolitis.

J A Gruskay, S Abbasi, E Anday

    The Journal of Pediatrics
    |September 1, 1986
    PubMed
    Summary
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    Staphylococcus epidermidis bacteremia is linked to mild enterocolitis in neonates. This finding is important for guiding antibiotic selection in neonatal intensive care units.

    Area of Science:

    • Neonatal Medicine
    • Infectious Diseases
    • Gastroenterology

    Background:

    • Neonatal enterocolitis is a serious condition.
    • Staphylococcus epidermidis is a common cause of sepsis in neonates.

    Purpose of the Study:

    • To investigate the association between Staphylococcus epidermidis bacteremia and enterocolitis in neonates.
    • To characterize the clinical presentation and outcomes of S. epidermidis-associated enterocolitis.

    Main Methods:

    • Retrospective chart review of 19 infants with S. epidermidis bacteremia and enterocolitis.
    • Analysis of clinical signs, symptoms, radiographic findings, and laboratory results.

    Main Results:

    • S. epidermidis-associated enterocolitis was relatively mild compared to other forms.

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  • Abnormal bowel gas patterns were common, but severe complications like pneumatosis intestinalis were rare.
  • Most infants did not require surgical intervention and had no prolonged feeding intolerance or stricture development.

    • Conclusions:

    • Staphylococcus epidermidis infection is frequently associated with a mild form of neonatal enterocolitis.
    • This association should be considered when choosing antibiotics for neonatal sepsis and enterocolitis.