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Updated: Jul 23, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
Kawasaki Disease Associated with SARS-CoV2 in a Pair of Triplets
Luisa Berenise Gamez-Gonzalez1,2, Luis Xochihua-Díaz3, Moises Ramirez-Lopez2
1Allergy and Immunology Department, Hospital Infantil de Especialidades de Chihuahua, Chihuahua, Mexico.
Abstract:
The etiology of Kawasaki disease (KD) and its precise genetic basics remain unknown. Genetic variants affecting immunity have been found in some patients. The occurrence of KD in siblings is rare, but KD pedigrees with multiple affected members have been described in Japan and North America. Cases in twins have been documented. We report 2 pairs of trizygotic triplets who developed KD associated with SARS-CoV2 infection from 2 different families. Our cases show that KD is multifactorial in origin, and both infectious etiology (particularly SARS-CoV2 as in our cases) and genetic factors are relevant in the disease.
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