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Updated: Jul 23, 2025

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Intracranial arachnoid cysts.

A Karim Ahmed1, Alan R Cohen2

  • 1Department of Neurosurgery, Johns Hopkins Hospital, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Phipps 566, Baltimore, MD, 21287, USA.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|July 19, 2023
PubMed
Summary
This summary is machine-generated.

This review details intracranial arachnoid cysts, congenital brain lesions. It covers their natural history, causes, and surgical management strategies for optimal patient care.

Keywords:
Arachnoid cystInterhemispheric cystMiddle fossa cystPosterior fossa cystQuadrigeminal cystRetrocerebellar cystSuprasellar cyst

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Area of Science:

  • Neurology
  • Neurosurgery
  • Developmental Biology

Background:

  • Intracranial arachnoid cysts are congenital lesions arising from split arachnoid membranes.
  • Etiology is multifactorial, with increased incidence in males and association with genetic syndromes.
  • Commonly found incidentally in the middle cranial fossa, but also occur in other intracranial locations.

Approach:

  • Comprehensive literature review utilizing Embase, PubMed, and Web of Science.
  • Inclusion of 59 relevant original articles and author's clinical experience.
  • Focus on natural history, pathogenesis, anatomical considerations, and surgical decision-making.

Key Points:

  • Cyst wall composition includes thick collagen and hyperplastic arachnoid cells.
  • Associated genetic conditions include Down syndrome, neurofibromatosis, and ADPKD.
  • Prevalence and demographic factors are outlined for better understanding.

Conclusions:

  • This review provides a comprehensive overview of intracranial arachnoid cysts.
  • It aims to guide clinicians in surgical decision-making and patient management.
  • Understanding natural history and pathogenesis is crucial for effective treatment.