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Updated: Jul 24, 2026

Combination Radiotherapy in an Orthotopic Mouse Brain Tumor Model
Published on: March 6, 2012
Meningioma and glioma as the first collision brain tumour reported in small animals
Marta Pons-Sorolla Casanova1, Alba Farré Mariné1, Martí Pumarola I Batlle2
1AUNA Especialidades Veterinarias IVC Evidensia, Carrer de l'Algepser, Paterna, Valencia, 46980, Spain.
Abstract:
We describe the clinical and pathological features of a brain collision tumour consisting of a fibrous meningioma and an anaplastic oligoastrocytoma in a 14-year-old male neutered French Bulldog. Computed tomography of the brain revealed a poorly defined, intra-axial lesion affecting the left frontal lobe. Following euthanasia, histological examination showed an anaplastic oligoastrocytoma invading the brain parenchyma and an adjacent fibrous meningioma. As synchronous intracranial tumours are rare in animals, the aims of this report are to describe the clinical, imaging and histopathological features of an intracranial collision tumour in a dog and highlight the importance of a complete histopathological study despite the imaging findings.
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