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Arterial Spin Labeling (ASL) in Neuroradiological Diagnostics - Methodological Overview and Use Cases.

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Arterial spin labeling (ASL) is an MRI technique for brain perfusion imaging, assessing cerebral blood flow (CBF) without contrast agents. It shows promise for various CNS diseases and specific patient groups.

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Neuroimaging Techniques
  • Cerebral Perfusion Assessment

Background:

  • Arterial spin labeling (ASL) utilizes labeled blood-water as an endogenous tracer for brain perfusion imaging.
  • ASL enables the non-invasive assessment of cerebral blood flow (CBF).

Conclusions:

  • ASL perfusion imaging shows significant promise for various CNS diseases.
  • ASL is advantageous as it avoids gadolinium-based contrast agents, benefiting specific patient cohorts.
  • ASL is particularly valuable for pediatric patients, those with kidney dysfunction, allergies, or requiring serial monitoring.