Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging
Ellen M Quardokus1, Diane C Saunders2,3, Elizabeth McDonough4
1Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.
Nature Methods
|July 19, 2023
Abstract:
Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods. Organ mapping antibody panels are community-validated resources that save time and money, increase reproducibility, accelerate discovery and support the construction of a Human Reference Atlas.


