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Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
Sanjay Jain1,2,3, Liming Pei4, Jeffrey M Spraggins5
1Department of Medicine, Washington University School of Medicine, St Louis, MO, USA. sanjayjain@wustl.edu.
Nature Cell Biology
|July 19, 2023
Summary
The Human BioMolecular Atlas Program (HuBMAP) is creating a detailed spatial map of the human body at single-cell resolution. This initiative will provide essential tools and data to advance biomedical research and understanding of human tissues.
Area of Science:
- Human biology
- Biomedical research
- Spatial omics
Background:
- The Human BioMolecular Atlas Program (HuBMAP) has completed its initial phase, focusing on ontologies, protocols, and pipelines.
- The program aims to create a comprehensive spatial atlas of the human body.
Purpose of the Study:
- To introduce the production phase of the HuBMAP initiative.
- To detail the generation of reference spatial maps of functional tissue units.
- To develop mapping tools and infrastructure for biomedical research.
Main Methods:
- Application of advanced technologies for spatial mapping.
- Generation of single-cell resolution data.
- Integration of data from diverse organs and populations.
Main Results:
- The perspective outlines the transition to the production phase of HuBMAP.
- Focus on creating multi-scale spatial atlases of human tissues.
- Development of new tools and infrastructure is underway.
Conclusions:
- The HuBMAP production phase will generate valuable spatial maps and resources.
- These resources will significantly advance biomedical research.
- The program emphasizes community dissemination of data and tools.
