Recent Advances for Dynamic-Based Therapy of Atherosclerosis

Area of Science:

• Biomedical Engineering
• Nanomedicine
• Materials Science

Background:

• Atherosclerosis (AS) is a chronic inflammatory disease with high morbidity and mortality.
• Current treatments (drugs, surgery) have deficient therapeutic effects, necessitating advanced strategies.
• Nanomedicine and energy conversion materials show promise for treating major diseases.

Purpose of the Study:

• To review recent advances in energy conversion-based nano-therapies for atherosclerosis.
• To summarize therapeutic effects and highlight regulated pathological processes.
• To discuss challenges and prospects for dynamic anti-atherosclerosis treatments.

Main Methods:

• Focus on energy conversion-based nanomaterials (organic/inorganic).
• Utilize nanomaterials with specific physiochemical properties activated by external stimuli (light, ultrasound).
• Target pathological characteristics of vulnerable atherosclerotic plaques.

Main Results:

• Nanomaterials promote foam cell apoptosis and cholesterol efflux.
• Energy conversion nano-therapy shows increasing attention for anti-atherosclerosis.
• Various techniques demonstrate therapeutic effects on regulated pathological processes.

Conclusions:

• Energy conversion-based nano-therapy represents a promising frontier in anti-atherosclerosis treatment.
• Further development is needed to address challenges in dynamic treatment strategies.
• This approach offers hope for improved patient outcomes in managing atherosclerosis.