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Updated: Jul 23, 2025

A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
Long-term effectiveness, outcomes and complications of bariatric surgery
Milena Gulinac1, Dimitrina Georgieva Miteva2, Monika Peshevska-Sekulovska3
1Department of General and Clinical Pathology, Medical University of Plovdiv, Plovdiv 4000, Bulgaria. mgulinac@hotmail.com.
Abstract:
Dietary imbalance and overeating can lead to an increasingly widespread disease - obesity. Aesthetic considerations aside, obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases, including diabetes; hypertension; atherosclerosis; coronary artery disease and stroke; obstructive sleep apnea; depression; weight-related arthropathies and endometrial and breast cancer. A body weight 20% above ideal for age, gender and height is a severe health risk. Bariatric surgery is a set of surgical methods to treat morbid obesity when other treatments such as diet, increased physical activity, behavioral changes and drugs have failed. The two most common procedures currently used are sleeve gastrectomy and gastric bypass. This procedure has gained popularity recently and is generally considered safe and effective. Although current data show that perioperative mortality is low and better control of comorbidities and short-term complications is achieved, more randomized trials are needed to evaluate the long-term outcomes of bariatric procedures. This review aims to synthesize and summarize the growing evidence on the long-term effectiveness, outcomes and complications of bariatric surgery.
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