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Predictive factors for persistent postoperative hydrocephalus in children undergoing surgical resection of

Zitao Chen1, Ming Zhou1, Huantao Wen1

  • 1The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Frontiers in Neurology
|July 20, 2023
PubMed

Insights

Predictors of persistent hydrocephalus in children after periventricular tumor resection include surgical approach, extent of resection, and tumor volume. Early cerebrospinal fluid (CSF) intervention is crucial for reducing complications.

Area of Science:

  • Pediatric Neurosurgery
  • Oncology
  • Neurology

Background:

  • Periventricular tumors in children can lead to hydrocephalus post-surgery.
  • Cerebrospinal fluid (CSF) diversion is a common intervention.

Purpose of the Study:

  • Identify factors predicting persistent hydrocephalus after periventricular tumor resection in children.
  • Assess the need and efficacy of perioperative CSF intervention.

Main Methods:

  • Retrospective analysis of 117 pediatric patients undergoing periventricular tumor resection.
  • Analysis of demographic, radiographic, perioperative, and dispositional data using univariate and multivariate models.

Main Results:

  • Incidence of hydrocephalus varied with tumor pathology, location, surgical approach, resection extent, tumor volume, preoperative Evan's index, and CSF diversion.
  • Independent predictors included posterior median approach, partial resection, tumor volume > 90cm³, and no preoperative CSF diversion.

Conclusions:

  • Posterior median approach, partial resection, and large tumor volume (>90cm³) without preoperative CSF diversion are independent risk factors for persistent hydrocephalus.
  • Preoperative identification and intervention for hydrocephalus can prevent delays and reduce the incidence of persistent hydrocephalus and shunt surgery.
Abstract

Keywords:
CSF managementhydrocephaluspediatric brain tumorsrisk factorssurgical treatment

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