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Updated: Jul 23, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
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Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms

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Pharmacokinetics during therapeutic hypothermia in neonates: from pathophysiology to translational knowledge and

Karen Leys1, Marina-Stefania Stroe2, Pieter Annaert1,3

  • 1Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences KU Leuven, Leuven, Belgium.

Expert Opinion on Drug Metabolism & Toxicology
|July 20, 2023
PubMed
Abstract

Keywords:
Göttingen minipigPBPKneonatal pathophysiologyperinatal asphyxiapharmacotherapyphysiologically-based pharmacokinetic modelingtherapeutic hypothermia

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