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Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
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The Transactions of the Esculapian Society of the Wabash Valley, at Its Annual Session Held at Tuscola, Illinois, October 26-7, 1870.

Chicago medical examiner·2023
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Primary Culture of Human Vestibular Schwannomas
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Wabash Valley Æsculapian Society

M W Wilcox1, Wm E Henry2

  • 1President; Mattoon, Ill.

Chicago Medical Examiner
|July 20, 2023
PubMed
Summary

No abstract available in PubMed .

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