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Updated: Jul 22, 2025

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
Trans-2,3-enoyl-CoA reductase-like-related catecholaminergic polymorphic ventricular tachycardia with regular
Mohammad A Ebrahim1, Ali A Alkhabbaz2, Buthaina Albash3
1Department of Pediatrics, Affiliated with Chest Diseases Hospital, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
Introduction:
We describe a unique case of TECRL-CPVT presented with cardiac arrest.
Methods:
Post resuscitation, the patient developed regular ventricular tachycardia featuring a left purkinje system morphology.
Results:
There was clear suppression of arrhythmia with the addition of flecainide and isolated ventricular ectopy causing secondary T-wave changes.
Conclusion:
A high index of suspicion was required to eventually make the diagnosis through whole exome sequencing.
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