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Related Concept Videos

Ferromagnetism01:31

Ferromagnetism

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Materials like iron, nickel, and cobalt consist of magnetic domains, within which the magnetic dipoles are arranged parallel to each other. The magnetic dipoles are rigidly aligned in the same direction within a domain by quantum mechanical coupling among the atoms. This coupling is so strong that even thermal agitation at room temperature cannot break it. The result is that each domain has a net dipole moment. However, some materials have weaker coupling, and are ferromagnetic at lower...
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A Random-displacement Measurement by Combining a Magnetic Scale and Two Fiber Bragg Gratings
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Submillimeter Multifunctional Ferromagnetic Fiber Robots for Navigation, Sensing, and Modulation.

Yujing Zhang1, Xiaobo Wu2,3, Ram Anand Vadlamani4

  • 1Bradley Department of Electrical and Computer Engineering, Virginia Tech, Blacksburg, VA, 24061, USA.

Advanced Healthcare Materials
|July 20, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed submillimeter fiber robots for biomedical use. These remotely controlled robots integrate navigation, sensing, and treatment, enabling minimally invasive procedures in complex environments.

Keywords:
biomedical engineeringferromagnetic roboticsfiber robotsmicro roboticsthermal drawing

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Area of Science:

  • Biomedical Engineering
  • Robotics
  • Materials Science

Background:

  • Current small-scale robots face limitations in miniaturization and functional integration for biomedical applications.
  • Need for advanced robotic platforms for targeted diagnostics and therapeutics in complex biological systems.

Purpose of the Study:

  • To present submillimeter fiber robots with integrated navigation, sensing, and modulation capabilities.
  • To demonstrate a scalable manufacturing process for these advanced biomedical robots.
  • To validate their utility in complex environments and for targeted medical interventions.

Main Methods:

  • Fabrication using a scalable thermal drawing process, integrating ferromagnetic, electrical, optical, and microfluidic composites.
  • Characterization of fiber robot dimensions (250 µm diameter, 150 m length) and magnetic actuation (54° deflection at 45 mT).
  • Testing in artificial vessels, brain phantoms, Langendorff mouse hearts, glioblastoma models, and in vivo mouse models.

Main Results:

  • Successful integration of multiple functionalities into submillimeter fiber robots.
  • Demonstrated remote navigation and precise steering in constrained and complex biological phantoms and models.
  • Validated capabilities for sensing electrophysiology signals and delivering localized treatment, including endoscopic functions.

Conclusions:

  • The developed fiber robots offer a versatile platform for multimodal detection and treatment.
  • Enables minimally invasive and remotely controlled interventions at hard-to-reach anatomical locations.
  • Presents a significant advancement for targeted therapies and diagnostics in the biomedical field.