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Severe Congenital Heart Defects and Cerebral Palsy

Ester Garne1, Shona Goldsmith2, Ingeborg Barisic3

  • 1Department of Pediatrics and Adolescent Medicine, Lillebaelt Hospital, University Hospital of Southern Denmark, Kolding, Denmark.

The Journal of Pediatrics
|July 20, 2023
PubMed

Insights

Children with severe congenital heart defects (sCHD) have a higher prevalence of cerebral palsy (CP). However, CP in these children tends to be milder than in those without congenital anomalies.

Area of Science:

  • Pediatric Neurology
  • Cardiology
  • Developmental Pediatrics

Background:

  • Cerebral palsy (CP) is a significant neurodevelopmental disorder.
  • Severe congenital heart defects (sCHD) are a known risk factor for adverse neurodevelopmental outcomes.
  • Understanding the interplay between sCHD and CP is crucial for early intervention and management.

Purpose of the Study:

  • To determine the prevalence of cerebral palsy (CP) in children with severe congenital heart defects (sCHD).
  • To describe the outcome and severity of CP in children with sCHD.
  • To compare CP characteristics in children with and without sCHD.

Main Methods:

  • A population-based data linkage study utilizing CP and congenital anomaly registers.
  • Inclusion of data from 4 European and 2 Australian regions (1991-2009).
  • Application of the EUROCAT definition for severe CHD (sCHD).

Main Results:

  • The prevalence of CP was 2.9 per 1000 births; sCHD prevalence was 2.1 per 1000 births.
  • 1.5% of children with sCHD also had CP (n=57).
  • Children with CP and sCHD more frequently presented with unilateral spastic CP and intellectual impairments compared to children with CP alone.

Conclusions:

  • The proportion of children with CP is significantly higher in those with sCHD compared to the general population.
  • CP in children with sCHD appears to be milder in severity than in children with CP without congenital anomalies.
  • This highlights the importance of neurodevelopmental surveillance in pediatric cardiology patients.
Abstract

Keywords:
CHDbrain injurycerebral palsyintellectual impairmentseverity

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