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Non-invasive and Locally Invasive Hypercellular Peripheral Odontogenic Fibroma in 20 Dogs
Inshil Kim1, Mary K Volker1, Barbara Powers2
1Animal Dental Center, Towson, MD, USA.
Journal of Veterinary Dentistry
|July 21, 2023
Summary
This study reclassifies canine odontogenic sarcomas as hypercellular peripheral odontogenic fibromas. These canine tumors showed no recurrence after surgical removal, suggesting a favorable prognosis.
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Oral Tumors
Background:
- Odontogenic sarcomas are rare malignant tumors in dogs.
- Accurate histopathological classification is crucial for prognosis and treatment.
Purpose of the Study:
- To re-evaluate canine tumors initially diagnosed as odontogenic sarcoma.
- To characterize their histopathological features and clinical behavior.
Main Methods:
- Retrospective review of medical records from 20 dogs.
- Detailed analysis of signalment, clinical signs, diagnostic imaging, surgical procedures, and histology.
- Rigorous histological re-evaluation.
Main Results:
- Twenty dogs met the criteria for reclassification.
- Tumors exhibited hypercellularity, mitotic activity, and variable odontogenic epithelium/hard substance.
- Proposed new classification: non-invasive or locally invasive hypercellular peripheral odontogenic fibroma.
- No recurrence observed post-surgery.
Conclusions:
- Canine odontogenic sarcomas may represent a distinct entity, potentially hypercellular peripheral odontogenic fibromas.
- Surgical excision appears curative with no observed recurrence.
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