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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
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Isolated Tuberculous Myositis: A Systematic Review and Multicenter Cases.

Ji Hyoun Kim1, Jeong Seok Lee2, Byoong Yong Choi3

  • 1Division of Rheumatology, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.

Journal of Rheumatic Diseases
|July 21, 2023
PubMed
Summary
This summary is machine-generated.

Isolated tuberculous myositis (ITBM) presents uniquely and has severe outcomes, particularly in immunocompromised individuals. Dermatomyositis/polymyositis is a common underlying condition in these rare extrapulmonary tuberculosis cases.

Keywords:
DermatomyositisInfectious myositisMycobacterium tuberculosisPolymyositis

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Area of Science:

  • Infectious Diseases
  • Rheumatology
  • Pulmonology

Background:

  • Isolated tuberculous myositis (ITBM) is a rare form of extrapulmonary tuberculosis.
  • Understanding its clinical features and associated conditions is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate the clinical features and underlying conditions of isolated tuberculous myositis (ITBM).
  • To analyze the outcomes of ITBM, especially in immunocompromised patients.

Main Methods:

  • A systematic literature search and a multicenter survey were conducted.
  • Data from identified ITBM cases were extracted and analyzed for underlying conditions, presentations, treatments, and outcomes.

Main Results:

  • 58 ITBM cases (9 pediatric) were identified. Immunocompromised patients had shorter symptom duration and higher multilocular involvement.
  • Dermatomyositis/polymyositis (DM/PM) was a common underlying disease in immunocompromised adults with ITBM.
  • ITBM had a grave outcome, especially in immunocompromised hosts, with higher mortality in survey-identified cases.

Conclusions:

  • ITBM presents uniquely with fever, tenderness, swelling, erythema, and abscess formation.
  • DM/PM is a highly prevalent underlying disease in immunocompromised ITBM patients.
  • ITBM poses a significant risk, particularly for immunocompromised individuals.