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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
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Coarctation of the Aorta: Modern Paradigms Across the Lifespan

Katherine B Salciccioli1, Justin P Zachariah2

  • 1Section of Pediatric Cardiology, Departments of Internal Medicine and Pediatrics (K.B.S.), Baylor College of Medicine, Texas Children's Hospital, Houston.

Hypertension (Dallas, Tex. : 1979)
|July 21, 2023
PubMed

Insights

Coarctation of the aorta increases hypertension risk throughout life, even after repair. This review covers lifelong management and hypertension mechanisms for repaired coarctation of the aorta patients.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Vascular Surgery

Background:

  • Coarctation of the aorta (CoA) presents with variable severity and age.
  • Hypertension is a significant risk for patients with CoA, persisting before and after surgical repair.
  • Despite advancements, long-term cardiovascular disease risk remains elevated in repaired CoA patients.

Purpose of the Study:

  • To provide a comprehensive overview of coarctation of the aorta management across all age groups.
  • To elucidate the pathophysiologic mechanisms underlying hypertension in CoA patients.
  • To discuss critical long-term follow-up considerations for individuals with repaired CoA.

Main Methods:

  • This is a review article.
  • Literature search on coarctation of the aorta management, hypertension, and long-term outcomes.
  • Synthesis of current knowledge on genetic etiologies, pathophysiology, and repair strategies.

Main Results:

  • Coarctation of the aorta requires lifelong monitoring due to persistent hypertension risk.
  • Understanding pathophysiologic mechanisms is key to managing hypertension post-repair.
  • Long-term follow-up protocols are essential for preventing acquired cardiovascular disease.

Conclusions:

  • Lifelong management and monitoring are crucial for patients with coarctation of the aorta.
  • Addressing the pathophysiologic basis of hypertension can improve patient outcomes.
  • Proactive long-term follow-up strategies mitigate the risk of future cardiovascular events.

Keywords:
aortacoarctationcongenital heart diseasehypertension

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