Electrophysiological assessment of monoamine synaptic function in neuronal circuits of seizure susceptible brains

The following report reviews evidence suggesting a role for the monoamines, norepinephrine (NE) and serotonin (5-HT), in the pathophysiology of seizure disorders and outlines a strategy for electrophysiologically evaluating monoaminergic function at the synaptic level in central neuronal circuits of two animal models of epilepsy.