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Updated: Jul 22, 2025

Structural Biology and Analytical Chemistry Approaches for Characterizing C-Glycoside Metabolic Enzymes in Human Gut Microbiota
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Purine-ifying uric acid by gut microbes

Agnieszka Grelska1, Deepti Sharan1, Samuel H Light1

  • 1Duchossois Family Institute, University of Chicago, Chicago, IL, USA; Department of Microbiology, University of Chicago, Chicago, IL, USA.

Cell Chemical Biology
|July 21, 2023
PubMed
Summary

Gut microbes break down purines, lowering uric acid levels in the blood. This discovery reveals a new way the gut microbiome influences host health, impacting diseases like gout and atherosclerosis.

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