Related Experiment Video
Updated: Jul 22, 2025

Establishment of Deep Hypothermic Circulatory Arrest in Rats
Published on: December 16, 2022
Sedation and shivering management after cardiac arrest
Bram J Geller1, Carolina B Maciel2, Teresa L May3
1Department of Cardiovascular Medicine and Cardiovascular Critical Care Services, Maine Medical Center, Portland, ME, USA.
Managing sedation and shivering during targeted temperature management (TTM) after cardiac arrest requires careful consideration. This review outlines best practices for optimizing patient care and outcomes during TTM protocols.
Area of Science:
- Critical Care Medicine
- Neuroscience
- Pharmacology
Background:
- Effective sedation and shivering management are crucial for targeted temperature management (TTM) post-cardiac arrest.
- Limited high-quality evidence exists, necessitating extrapolation from general intensive care unit (ICU) data with caution.
Approach:
- Review of current literature and clinical best practices for sedation and shivering control in post-cardiac arrest patients.
- Consideration of unique physiological changes and treatment goals in this specific patient population.
Key Points:
- Sedation goals in post-cardiac arrest differ from general ICU patients, often including shivering suppression during TTM.
- Altered drug metabolism during TTM can impact clearance and neuroprognostication.
- Deep or prolonged sedation may lead to complications like delirium, infections, and delayed neurological assessment.
Conclusions:
- Optimizing sedation and shivering management is vital for improving outcomes in post-cardiac arrest patients undergoing TTM.
- Clinicians must balance the need for adequate sedation and shivering control with the risks of prolonged or excessive sedation.
Related Concept Videos
Cardiopulmonary Resuscitation IV: Pharmacological Management
Stages of General Anesthesia
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Dysrhythmias VII: Nursing Management of Dysrhythmias
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Acute Coronary Syndrome V: Nursing Management

