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From Bariatric Surgery to Conception: The Ideal Timing to Optimize Fetal Weight
Ana Carreira1, Bárbara Araújo2, Mariana Lavrador2,3
1Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar E Universitário de Coimbra, 3004-561, Coimbra, Portugal. 11720@chuc.min-saude.pt.
Obesity Surgery
|July 22, 2023
Summary
Waiting at least 24 months after bariatric surgery (BS) significantly reduces the risk of small for gestational age (SGA) neonates. Longer surgery-to-conception intervals (BSCI) are associated with increased birth weight and decreased SGA risk.
Area of Science:
- Obstetrics and Gynecology
- Bariatric Surgery Outcomes
- Neonatal Health
Background:
- Bariatric surgery (BS) is linked to an increased risk of small for gestational age (SGA) neonates.
- Current guidelines suggest a 12-24 month interval between BS and conception, but optimal timing is unclear.
Purpose of the Study:
- To evaluate the impact of the surgery-to-conception interval (BSCI) on neonatal birth weight and the risk of SGA.
- To determine an optimal BSCI to mitigate adverse neonatal outcomes.
Main Methods:
- Retrospective cohort study of 42 pregnancies post-bariatric surgery.
- Neonates classified as SGA if birth weight <10th percentile.
- ROC curve analysis to establish optimal BSCI cut-off.
Main Results:
- A linear association was found between BSCI and birth weight (4.5g increase per month).
- An inverse association between BSCI and SGA risk (-6% per month).
- A BSCI of 24.5 months was identified as optimal; pregnancies within 24 months had a >10-fold increased SGA risk (OR 12.6).
Conclusions:
- The surgery-to-conception interval (BSCI) significantly impacts birth weight and SGA risk.
- A minimum BSCI of 24 months is recommended to reduce the risk of SGA neonates following bariatric surgery.
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