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The burden of cardiovascular disease attributable to high body mass index-an observational study
Xin-Jiang Dong1, Xiao-Qi Zhang2, Bei-Bei Wang3
1Department of Cardiology, Shanxi Cardiovascular Hospital, No. 18 Yifen Street, Wanbailin District, Taiyuan 030024, China.
Insights
Cardiovascular disease (CVD) deaths and disability linked to high body mass index (HBMI) have doubled globally since 1990. However, age-standardized rates are declining, with varying trends across regions and socioeconomic statuses.
Area of Science:
- Epidemiology
- Public Health
- Cardiology
Background:
- High body mass index (HBMI) is a significant risk factor for cardiovascular diseases (CVD).
- Understanding the global burden and trends of CVD attributable to HBMI is crucial for public health interventions.
Purpose of the Study:
- To estimate the current burden and temporal trends of CVD attributable to HBMI globally.
- To analyze these trends by various demographic and socioeconomic factors.
Main Methods:
- Systematic assessment using Global Burden of Disease Study (GBD) 2019 data.
- Analysis by calendar year, age, sex, region, nation, socioeconomic status, and specific CVDs.
- Calculation of disability-adjusted life years (DALYs) and deaths, and age-standardized rates (ASRs).
Main Results:
- Global CVD DALYs and deaths attributed to HBMI more than doubled between 1990 and 2019.
- Age-standardized rates (ASRs) showed a slight downward trend (-0.18% for DALYs, -0.43% for deaths annually).
- Higher burden in middle/high-middle SDI regions, with downward ASR trends in high SDI and upward trends in low/low-middle SDI regions. Leading causes: ischemic heart disease, stroke, hypertensive heart disease, atrial fibrillation/flutter.
Conclusions:
- CVD burden attributable to HBMI is a persistent global health challenge.
- Targeted strategies are needed, with lessons from regions experiencing decreasing burdens.
- Policymakers should focus on high and increasing burden regions for tailored prevention efforts.
Aim:
This study aims to provide a timely and comprehensive estimate of the current burden and temporal trend of cardiovascular disease (CVD) attributable to high body mass index (HBMI).
Methods:
We systematically assessed the current burden and temporal trend of CVD attributable to HBMI by calendar year, age, sex, region, nation, socioeconomic status, and specific CVD based on the most recent Global Burden of Disease Study (GBD) 2019.
Results:
Globally, the numbers of CVD-related disability-adjusted life years (DALYs) and deaths attributable to HBMI has more than doubled from 1990 to 2019. Conversely, the age-standardized rates (ASRs) of CVD-related DALYs and deaths attributable to HBMI showed a slight downward trend, with estimated annual percentage change (EAPC) of -0.18 and -0.43, respectively. The ASRs of CVD-related DALYs and deaths attributable to HBMI were lower in low and high Socio-demographic Index (SDI) regions in 2019, but higher in middle and high-middle SDI regions. The ASRs of CVD-related DALYs and deaths attributable to HBMI showed a downward trend in the high SDI regions from 1990 to 2019, but showed an upward trend in the low and low-middle SDI regions. The leading causes of CVD burden attributable to HBMI were ischemic heart disease, stroke, hypertensive heart disease, and atrial fibrillation/flutter in 2019.
Conclusion:
The CVD burden attributable to HBMI remains a challenging global health concern. Policymakers in high and increasing burden regions can learn from some valuable experiences of low and decreasing burden regions and develop more targeted and specific strategies to prevent and reduce CVD burden attributable to HBMI.
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